Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.41 |
| ▸ | PDE4A | P27815 | 9/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249453 | 0.94 | PDE4B (0.34) | PDE4BPDE4APDE4CPDE4DPDE5A | |
| SCHEMBL3201072 | 0.86 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DLPAR1 | |
| SCHEMBL3118118 | 0.85 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DLTC4S | |
| SCHEMBL3131319 | 0.84 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DLPAR1 | |
| SCHEMBL3209523 | 0.83 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DLPAR1 | |
| SCHEMBL3117980 | 0.82 | PDE4D (0.53) | PDE4BPDE4APDE4CPDE4DLPAR1 | |
| SCHEMBL3203543 | 0.81 | PDE4D (0.47) | PDE4BPDE4APDE4CPDE4DLPAR1 | |
| SCHEMBL3126139 | 0.81 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DLPAR1 | |
| SCHEMBL3213634 | 0.80 | CA12 (0.35) | — | |
| SCHEMBL3202535 | 0.78 | PDE4D (0.49) | PDE4BPDE4APDE4CPDE4DLTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |