SCHEMBL3249508

SCHEMBL3249508

COCC1CC(OS(C)(=O)=O)CN1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.35
ANPEP P15144 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26086744 1.00 MMP2 (0.35) MMP2ANPEP
SCHEMBL3945766 1.00 MMP2 (0.35) MMP2ANPEP
SCHEMBL18426092 0.90 MMP2 (0.33) MMP2ANPEP
SCHEMBL3950857 0.86 MMP2 (0.32) MMP2ANPEP
SCHEMBL19898240 0.85 MMP2 (0.34) MMP2ANPEP
SCHEMBL28593603 0.85 MMP2 (0.34) MMP2ANPEP
SCHEMBL5078017 0.84 FFAR1 (0.31)
SCHEMBL23632051 0.83 MMP2 (0.31) MMP2ANPEP
SCHEMBL1440010 0.82 NR1H2 (0.35) MMP2ANPEP
SCHEMBL9383870 0.82 NR1H2 (0.35) MMP2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1409463-B1 N-HETEROCYCLIC INHIBITORS OF TNF-ALPHA EXPRESSION BRISTOL MYERS SQUIBB CO (US) 2010-02-24 EP disclosed