Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094944 | 0.85 | OPRM1 (0.68) | OPRM1ACHEOPRD1OPRK1SLC22A1 | |
| SCHEMBL3083010 | 0.85 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Hydrochloric Acid SCHEMBL3089658 | 0.84 | OPRM1 (0.67) | OPRM1ACHEOPRD1OPRK1SLC22A1 | |
| SCHEMBL3089725 | 0.83 | OPRM1 (0.71) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL3089648 | 0.82 | OPRM1 (0.63) | OPRM1ACHEOPRD1OPRK1SLC22A1 | |
| SCHEMBL3081580 | 0.81 | OPRM1 (0.59) | OPRM1ACHEOPRD1OPRK1SLC22A1 | |
| SCHEMBL3091587 | 0.81 | OPRM1 (0.63) | OPRM1ACHEOPRD1OPRK1SLC22A1 | |
| SCHEMBL3091628 | 0.79 | OPRM1 (0.75) | OPRM1 | |
| SCHEMBL3088103 | 0.79 | OPRM1 (0.69) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL3087618 | 0.79 | OPRM1 (0.59) | OPRM1ACHEOPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | disclosed |