Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 15/20 | 1.00 |
| ▸ | NAMPT | P43490 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245134 | 0.88 | ROCK2 (0.79) | ROCK2NAMPTSMN1; SMN2NPC1 | |
| SCHEMBL3249295 | 0.87 | ROCK2 (0.78) | ROCK2NAMPT | |
| SCHEMBL13391170 | 0.87 | ROCK2 (0.78) | ROCK2 | |
| SCHEMBL3249431 | 0.87 | ROCK2 (1.00) | ROCK2NAMPT | |
| SCHEMBL3249722 | 0.85 | ROCK2 (1.00) | ROCK2NAMPT | |
| SCHEMBL3245013 | 0.85 | ROCK2 (0.80) | ROCK2NAMPT | |
| SCHEMBL17916794 | 0.83 | SMN1; SMN2 (0.88) | ROCK2NAMPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4511047 | 0.83 | ROCK2 (0.74) | ROCK2NAMPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3251290 | 0.81 | ROCK2 (0.74) | ROCK2 | |
| SCHEMBL26100778 | 0.81 | ROCK2 (0.67) | ROCK2NAMPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |