SCHEMBL3249571

SCHEMBL3249571

Clc1ccccc1-c1ccc(N2CCOCC2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 1.00
CNR1 P21554 1/20 0.59
RAB9A P51151 1/20 0.56
TDO2 P48775 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3248208 0.83 CNR2 (0.71) CNR2CNR1
SCHEMBL16773016 0.80 CNR2 (0.69) CNR2
SCHEMBL3648791 0.80 CNR2 (0.66) CNR2TDO2
SCHEMBL3239421 0.80 CNR2 (0.66) CNR2TDO2
SCHEMBL9987126 0.80 CNR2 (0.66) CNR2CNR1
SCHEMBL7704047 0.79 CNR2 (0.65) CNR2TDO2
SCHEMBL2169026 0.79 CNR2 (0.64) CNR2RAB9A
SCHEMBL13276366 0.78 CNR2 (0.64) CNR2RAB9A
SCHEMBL27667321 0.78 CNR2 (0.64) CNR2RAB9A
SCHEMBL29195938 0.78 CNR2 (0.64) CNR2TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010057833-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-05-27 WO claimed
WO-2010057833-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-05-27 WO disclosed