Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.56 |
| ▸ | PRKACA | P17612 | 3/20 | 0.53 |
| ▸ | PRKACG | P22612 | 3/20 | 0.53 |
| ▸ | PRKACB | P22694 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121519 | 0.95 | ROCK2 (0.69) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3243478 | 0.93 | ROCK2 (0.68) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3130421 | 0.91 | ROCK2 (0.70) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3244210 | 0.91 | ROCK2 (0.81) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL13391230 | 0.89 | ROCK2 (0.72) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3244989 | 0.87 | ROCK2 (0.64) | ROCK2ROCK1 | |
| SCHEMBL3241441 | 0.85 | ROCK2 (0.85) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3245577 | 0.84 | ROCK2 (0.76) | ROCK2ROCK1 | |
| SCHEMBL3247453 | 0.84 | ROCK2 (0.73) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3247086 | 0.84 | ROCK2 (0.73) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |