Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 12/20 | 0.36 |
| ▸ | CNR2 | P34972 | 11/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336863 | 0.90 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1339390 | 0.89 | CNR1 (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1339478 | 0.86 | CNR1 (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1339189 | 0.83 | GABRA1 (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL3256818 | 0.83 | EIF4E (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1338643 | 0.83 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1339468 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1337210 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1339526 | 0.80 | CNR1 (0.36) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1336976 | 0.80 | TRIM24 (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940840-B1 | 6-HETEROARYLPYRIDOINDOLONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-07-21 | — | — | EP | disclosed |