Arundine

Arundine

SCHEMBL325162

c1ccc2c(Cc3c[nH]c4ccccc34)c[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
GPR84 Q9NQS5 3/20 1.00
CYP3A4 P08684 3/20 1.00
AHR P35869 3/20 1.00
MAPT P10636 2/20 1.00
TDP1 Q9NUW8 1/20 1.00
HTR6 P50406 3/20 0.67
HTR2A P28223 4/20 0.64
CYP2D6 P10635 3/20 0.64
HTR2C P28335 3/20 0.64
HTR1D P28221 2/20 0.64
HTR1B P28222 2/20 0.64
HTR7 P34969 2/20 0.64
MPO P05164 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2A6 P11509 1/20 0.64
NFKB1 P19838 1/20 0.64
CTSK P43235 1/20 0.64
CYP2A13 Q16696 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arundine SCHEMBL28335217 0.98 MEN1 (0.95) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL553605 0.87 MEN1 (1.00) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL30648199 0.87 MEN1 (1.00) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL23144846 0.87 MEN1 (0.75) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL29202674 0.87 MEN1 (0.75) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL3132443 0.87 MEN1 (0.75) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL29989301 0.87 MEN1 (0.75) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL4985934 0.86 HTR2A (0.77) MEN1KMT2AGPR84CYP3A4AHR
SCHEMBL28273023 0.86 GPR84 (0.74) MEN1KMT2AGPR84CYP3A4AHR
Indole-3-Carbinol SCHEMBL2867957 0.84 MEN1 (0.72) MEN1KMT2AGPR84CYP3A4AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3812 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137715-A1 AQUEOUS FORMULATION INCLUDING DISSOLVED HYDROGEN GAS AND MINERALS AND ADDITIVES BEST PLANET SCIENCE LLC (US) 2026-05-21 US claimed
CN-117402100-B Preparation method of 3,3' -diindolylmethane and derivatives thereof participated by carbon dioxide 山西大学 2026-05-19 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP claimed
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 US claimed
EP-4694699-A2 COMPOSITIONS AND METHODS OF CONTROLLING MAMMALIAN SATIETY VitaKey Inc. (US) 2026-02-18 EP claimed
US-12527804-B2 Microemulsion delivery systems for alcohol-soluble species including DHEA, pregnenolone, and chrysin for reducing menopausal symptoms Quicksilver Scientific, Inc. (US) 2026-01-20 US claimed
US-12527765-B2 Composition comprising a diindolylmethane and a retinoid to treat a skin condition SKINTECH LIFE SCIENCE LIMITED (GB) 2026-01-20 US claimed
US-12527766-B2 Methods of treating acute coronary syndrome using 3,3′-diindolylmethane BOULDER BIOSCIENCE LLC (US) 2026-01-20 US claimed
EP-4676470-A2 DILEUCINE COMPOSITIONS AND METHODS OF USE THEREOF Ingenious Ingredients, LP (US) 2026-01-14 EP claimed
US-6544564-B1 Cytotoxic pharmaceutical composition FARLEY MICHAEL DONALD (US) 2003-04-08 US claimed
WO-2002080906-A1 PREVENTION AND TREATMENT OF ENDOMETRIOSIS WITH ARYL HYDROCARBON RECEPTOR BINDING LIGANDS CEDARS-SINAI MEDICAL CENTER (US) 2002-10-17 WO claimed
US-20020147155-A1 Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands CEDARS-SINAI MEDICAL CENTER 2002-10-10 US claimed
US-6399645-B1 Chemoprevention and treatment of cervical or vaginal neoplasia BELL MARIA (US) 2002-06-04 US claimed
US-20020058648-A1 Estrogenic substances combined with cruciferous indole compounds HAMMERLY MILTON (US) 2002-05-16 US claimed
WO-2002028832-A2 DIINDOLYLMETHANE AND C-SUBSTITUTED DIINDOLYLMETHANE COMPOSITIONS AND METHODS FOR THE TREATMENT OF MULTIPLE CANCERS THE TEXAS A & M UNIVERSITY SYSTEM (US) 2002-04-11 WO claimed
EP-1067913-A1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS Bioresponse, L.L.C. (US) 2001-01-17 EP claimed
US-6086915-A HEATING THE SOLUBILIZING EMULSIFIER, ADDING SOLVENT AND ONE OR MORE PHOSPHOLIPID SURFACTANTS, DISSOLVING IN THIS SOLUTION ONE OR MORE HYDROPHOBIC PHYTOCHEMICALS, ADDING ENCAPSULATORS, FORMING MICROEMULSION, SPRAY DRYING THE SOLUTION BIORESPONSE L.L.C. (US) 2000-07-11 US claimed
US-6001868-A ADMINISTERING TO AN INDIVIDUAL AN EFFECTIVE AMOUNT OF AN INDOLE-3-CARBINOL COMPOUND OR A DERIVATIVE TO TREAT TUMOR CELL GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-12-14 US claimed
WO-1999049851-A1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS BIORESPONSE, L.L.C. (US) 1999-10-07 WO claimed