Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245348 | 0.86 | HSD17B10 (0.69) | HSD17B10HPGDKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3255371 | 0.86 | HSD17B10 (0.49) | HSD17B10HPGDKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3243006 | 0.85 | HSD17B10 (0.47) | HSD17B10HPGDKMT2AMEN1MAPT | |
| SCHEMBL4156375 | 0.82 | HSD17B10 (0.54) | HSD17B10HPGDKMT2AMEN1MAPT | |
| SCHEMBL3247465 | 0.81 | CRHBP (0.47) | HSD17B10HPGDKMT2AMEN1MAPT | |
| SCHEMBL3246214 | 0.81 | HSD17B10 (0.55) | HSD17B10HPGDKMT2AMEN1MAPT | |
| SCHEMBL4161639 | 0.81 | HSD17B10 (0.52) | HSD17B10HPGDKMT2AMEN1MAPT | |
| SCHEMBL3255439 | 0.80 | HSD17B10 (0.54) | HSD17B10HPGDKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4174297 | 0.79 | HSD17B10 (0.51) | HSD17B10HPGDKMT2AMEN1MAPT | |
| SCHEMBL13928146 | 0.79 | HSD17B10 (0.53) | HSD17B10HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |