(+)-Secoisolariciresinol

(+)-Secoisolariciresinol

SCHEMBL325398

COc1cc(CC(CO)C(CO)Cc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 1.00
MMP1 P03956 1/20 1.00
FOS P01100 1/20 0.70
TTR P02766 1/20 0.70
JUN P05412 1/20 0.70
NR3C1 P04150 1/20 0.70
HSD17B1 P14061 1/20 0.70
HSD17B2 P37059 1/20 0.70
ALOX15 P16050 3/20 0.64
ALOX12 P18054 3/20 0.64
TSHR P16473 3/20 0.57
TAAR1 Q96RJ0 2/20 0.57
MAPK1 P28482 1/20 0.57
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
ALDH1A1 P00352 2/20 0.54
GAA P10253 2/20 0.54
NFKB1 P19838 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
PTPN1 P18031 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(+)-Secoisolariciresinol SCHEMBL12427083 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL21028109 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL20402961 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL30334899 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL31677395 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL29617981 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL29363814 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
(+)-Secoisolariciresinol SCHEMBL30605875 1.00 CYP3A4 (1.00) CYP3A4MMP1FOSTTRJUN
SCHEMBL29838368 0.95 CYP3A4 (0.91) CYP3A4MMP1FOSTTRJUN
SCHEMBL19413830 0.94 CYP3A4 (0.88) CYP3A4MMP1FOSTTRJUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2918 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
CN-116179407-B Enterococcus faecium and application thereof in bio-conversion of secoisolariciresinol diglucoside 暨南大学 2025-06-24 CN claimed
EP-4101437-B1 BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF SHENZHEN EULIKAN BIOTECHNOLOGY CO LTD (CN) 2025-06-11 EP claimed
US-20250170166-A1 HYALURONIC ACID HYDROGEL FORMULATION COMPRISING PHYTOESTROGEN FOR THE TREATMENT OF VAGINAL ATROPHY AND VAGINAL REJUVENATION AND PRODUCTION METHOD THEREOF VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI (TR) 2025-05-29 US claimed
US-12311001-B2 Use of extracellular vesicles of Rhizoma Drynariae in preparation of medicine for treating orthopedic diseases The Third Affiliated Hospital of Guangzhou University of Chinese Medicine (CN) 2025-05-27 US claimed
WO-2025104677-A1 COMPOSITIONS COMPRISING A CELL HYDROLYSATE AND POLYPHENOLS FOR TOPICAL APPLICATION AVANT MEATS COMPANY LIMITED (CN) 2025-05-22 WO claimed
CN-116179389-B Lactobacillus plantarum and application thereof in bio-transformation of secoisolariciresinol diglucoside 暨南大学 2025-05-16 CN claimed
CN-119745705-A Open-loop, different larch resin application of phenol in whitening 云南中医药大学 2025-04-04 CN claimed
US-12233101-B2 Compositions and methods useful in treatment of lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and other diseases or symptoms NATUREX INC. (US) 2025-02-25 US claimed
US-6264853-B1 PREPARING AQUEOUS ALIPHATIC ALCOHOLIC EXTRACT FROM FLAX AND SUBJECTING THIS AQUEOUS EXTRACT TO ULTRAFILTRATION USING MEMBRANE TO OBTAIN COMPLEX CONTAINING SECOISOLARICIRESINOL DIGLUCOSIDE, CINNAMIC ACID GLYCOSIDES AND HYDROXY METHYL AGRICULTURE AND AGRI-FOOD CANADA (CA) 2001-07-24 US claimed
US-6261565-B1 Method of preparing and using isoflavones ARCHER DANIELS MIDLAND COMPANY 2001-07-17 US claimed
WO-2001003687-A2 METHOD AND COMPOSITIONS FOR INHIBITING BIOSYNTHESIS OR BIOACTIVITY OF ENDOGENOUS STEROID SEX HORMONES IN HUMANS CEDARS-SINAI MEDICAL CENTER (US) 2001-01-18 WO claimed
WO-2000078771-A1 A COMPLEX CONTAINING LIGNAN, PHENOLIC AND ALIPHATIC SUBSTANCES FROM FLAX AND PROCESS FOR PREPARING HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE AND AGRI-FOOD CANADA (CA) 2000-12-28 WO claimed
EP-0906761-A2 Method of preparing and using phytochemicals ARCHER-DANIELS-MIDLAND COMPANY (US) 1999-04-07 EP claimed
US-5846944-A Purified SDG as an antioxidant THE UNIVERSITY OF SASKATCHEWAN (CA) 1998-12-08 US claimed
US-5837256-A USING SECOISOLARICIRESINOL NASCO INDUSTRIES INC. 1998-11-17 US claimed
EP-0817824-A2 PROCESS FOR EXTRACTING AND PURIFYING LIGNANS AND CINNAMIC ACID DERIVATIVES FROM FLAXSEED Her Majesty in Right of Canada, represented by The Minister of Agriculture and Agri-Food Canada (CA) 1998-01-14 EP claimed
US-5705618-A Process for extracting lignans from flaxseed AGRICULTURE AND AGRI-FOOD CANADA (CA) 1998-01-06 US claimed
WO-1996030468-A2 PROCESS FOR EXTRACTING AND PURIFYING LIGNANS AND CINNAMIC ACID DERIVATIVES FROM FLAXSEED HER MAJESTY IN RIGHT OF CANADA, represented by THEMINISTER OF AGRICULTURE AND AGRI-FOOD CANADA (CA) 1996-10-03 WO claimed