Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | MMP1 | P03956 | 1/20 | 1.00 |
| ▸ | FOS | P01100 | 1/20 | 0.70 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | JUN | P05412 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.70 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (+)-Secoisolariciresinol SCHEMBL21028109 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL20402961 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL30334899 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL31677395 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL29617981 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL29363814 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL30605875 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL325398 | 1.00 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| SCHEMBL29838368 | 0.95 | CYP3A4 (0.91) | CYP3A4MMP1FOSTTRJUN | |
| SCHEMBL19413830 | 0.94 | CYP3A4 (0.88) | CYP3A4MMP1FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| US-20230321197-A1 | Polyphenolic Insulin | KIMBALL WESTWARD LLC (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230256034-A1 | METHODS AND COMPOSITIONS FOR TREATING AUTOIMMUNE AND ALLERGIC DISORDERS | THE UNIVERSITY PF CHICAGO (US) | 2023-08-17 | — | — | US | disclosed |
| WO-2023118005-A1 | COMPOSITION CONTAINING THE COMBINATION OF A C-GLYCOSIDE AND ESCIN FOR THE CARE OF THE EYE AREA | L'OREAL (FR) | 2023-06-29 | — | — | WO | disclosed |
| US-10870670-B2 | Preparation of (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-22 | — | — | US | disclosed |
| US-10472688-B2 | Compositions and methods for producing podophyllotoxin derivatives | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190117555-A1 | SUBLINGUAL COMPOSITIONS COMPRISING NATURAL EXTRACTS AND USES THEREOF | HARMONIC PHARMA (FR) | 2019-04-25 | — | — | US | disclosed |
| US-10030040-B2 | Preparation of (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-07-24 | — | — | US | disclosed |
| US-20170088872-A1 | COMPOSITIONS AND METHODS FOR PRODUCING PODOPHYLLOTOXIN DERIVATIVES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2017-03-30 | — | — | US | disclosed |
| EP-2252154-B1 | METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL | OY GRANULA AB LTD (FI) | 2016-01-27 | — | — | EP | disclosed |
| US-20100129304-A1 | METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT | OY GRANULA AB LTD (FI) | 2010-05-27 | — | — | US | disclosed |
| US-20100129302-A1 | ANTIMICROBIAL COMPOSITION WITH LOW CYTOTOXICITY | OY GRANULA AB LTD (FI) | 2010-05-27 | — | — | US | disclosed |
| US-20100129302-A1 | ANTIMICROBIAL COMPOSITION WITH LOW CYTOTOXICITY | OY GRANULA AB LTD (FI) | 2010-05-27 | — | — | US | disclosed |
| US-20100129304-A1 | METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT | OY GRANULA AB LTD (FI) | 2010-05-27 | — | — | US | disclosed |
| US-20100031398-A1 | GENES ENCODING CHAVICOL/EUGENOL SYNTHASE FROM THE CREOSOTE BUSH LARREA TRIDENTATA | WASHINGTON STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2009101261-A2 | METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL | OY GRANULA AB LTD (FI) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009101262-A2 | METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT INHIBITING THE GROWTH OF MICRO-ORGANISMS AND FOR MAXIMIZING THE EFFECT | OY GRANULA AB LTD (FI) | 2009-08-20 | — | — | WO | disclosed |
| US-20080124414-A1 | Use Of Knotwood Extracts | OY ARBONOVA AB (FI) | 2008-05-29 | — | — | US | disclosed |
| US-20080124414-A1 | Use Of Knotwood Extracts | OY ARBONOVA AB (FI) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030040-B2 | Preparation of (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside | LSS, STS, SRM | CYP3A4 1606/4885MMP1 4402/4885FOS 513/4885 |
| US-20100129302-A1 | ANTIMICROBIAL COMPOSITION WITH LOW CYTOTOXICITY | CUTA, LCT, PYCARD | CYP3A4 1635/4885MMP1 425/4885FOS 2379/4885 |
| US-20080124414-A1 | Use Of Knotwood Extracts | SOD3, GPX1, GPX4 | CYP3A4 970/4885MMP1 189/4885FOS 3080/4885 |
| US-20100031398-A1 | GENES ENCODING CHAVICOL/EUGENOL SYNTHASE FROM THE CREOSOTE BUSH LARREA TRIDENTATA | CNOT1, CRAT, LRAT | CYP3A4 305/4885MMP1 4079/4885FOS 590/4885 |
| US-20190117555-A1 | SUBLINGUAL COMPOSITIONS COMPRISING NATURAL EXTRACTS AND USES THEREOF | SHBG, GYS1, PYGM | CYP3A4 880/4885MMP1 2073/4885FOS 4244/4885 |
| US-10870670-B2 | Preparation of (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside | LSS, STS, SRM | CYP3A4 1606/4885MMP1 4402/4885FOS 513/4885 |
| US-20100129304-A1 | METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, BAK1, PMAIP1 | CYP3A4 769/4885MMP1 1777/4885FOS 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.