SCHEMBL3256041

SCHEMBL3256041

O=C(O)CCCOc1ccc(F)cc1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.61
KDM4E B2RXH2 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PPARA Q07869 3/20 0.56
FFAR4 Q5NUL3 7/20 0.55
FFAR1 O14842 6/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PPARG P37231 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4401690 0.94 PPARA (0.63) LTA4HKDM4ESMN1; SMN2PPARAFFAR1
SCHEMBL4654976 0.93 PPARA (0.61) LTA4HKDM4ESMN1; SMN2PPARAFFAR1
SCHEMBL8863703 0.93 PPARA (0.61) LTA4HKDM4ESMN1; SMN2PPARAFFAR1
SCHEMBL1008370 0.93 PPARA (0.61) LTA4HKDM4ESMN1; SMN2PPARAFFAR1
SCHEMBL4654038 0.93 PPARA (0.61) LTA4HKDM4ESMN1; SMN2PPARAFFAR1
SCHEMBL7566062 0.92 PPARA (0.69) LTA4HKDM4ESMN1; SMN2PPARAFFAR4
SCHEMBL652824 0.90 L3MBTL1 (0.67) LTA4HKDM4ESMN1; SMN2PPARAFFAR1
SCHEMBL31448501 0.90 PPARA (0.65) PPARAFFAR4FFAR1L3MBTL1
SCHEMBL30530685 0.85 KDM4E (0.53) LTA4HKDM4ESMN1; SMN2
SCHEMBL31448470 0.84 PPARA (0.73) PPARAFFAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed
CN-118063452-A Benzothiazole or benzoxazole derivative and preparation method and application thereof 山东大学 2024-05-24 CN disclosed
EP-4216946-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Achillion Pharmaceuticals, Inc. (US) 2023-08-02 EP disclosed
CN-116437913-A Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2023-07-14 CN disclosed
WO-2022066774-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2022-03-31 WO disclosed
CN-113354590-A Quinazolinone compound for antagonizing NOD1/2 receptor signal pathway 宁波康柏睿格医药科技有限公司 2021-09-07 CN disclosed
CN-112624997-A Preparation method and application of 3-amino-2-oxazolidinone derivatives 中国人民解放军军事科学院军事医学研究院 2021-04-09 CN disclosed
EP-2029601-B1 PYRIDOPYRIMIDINONE DERIVATIVES HOFFMANN LA ROCHE (CH) 2010-06-02 EP disclosed
EP-1255166-B1 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KK (JP) 2009-12-16 EP disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20030072594-A1 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2003-04-17 US disclosed
EP-1255166-A2 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed
US-4086240-A 1-Thiazolyl-5-phenoxy and phenylthioalkanoyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1978-04-25 US disclosed
US-4053480-A 1-THIADIAZOLYL-5-PHENOXY- AND PHENYLTHIOALKANOYLOXY IMIDAZOLIDINONES VELSICOL CHEMICAL CORPORATION (US) 1977-10-11 US disclosed