Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252044 | 0.92 | GRIN1 (0.39) | GRIN2BGRIN1 | |
| SCHEMBL3247029 | 0.89 | GRIN2B (0.43) | GRIN2BGRIN1 | |
| SCHEMBL3249233 | 0.76 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL3252047 | 0.76 | GRIN1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL3122894 | 0.76 | GRIN1 (0.51) | GRIN2BGRIN1VEGFAFLT1EGLN1 | |
| SCHEMBL3247390 | 0.75 | GRIN2B (0.39) | GRIN2BGRIN1KMT2AVEGFAFLT1 | |
| SCHEMBL13521738 | 0.69 | GRIN1 (0.51) | GRIN2BGRIN1KMT2A | |
| SCHEMBL3241320 | 0.68 | GRIN1 (0.56) | GRIN2BGRIN1 | |
| SCHEMBL3242733 | 0.68 | GRIN1 (0.50) | GRIN2BGRIN1 | |
| SCHEMBL13521616 | 0.67 | GRIN2B (0.43) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |