SCHEMBL325637

SCHEMBL325637

CCC(C)(C)n1cccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12091666 0.79 TSHR (0.32) TSHRTDP1
SCHEMBL24692277 0.78
SCHEMBL12590858 0.77
SCHEMBL16719966 0.75
SCHEMBL2183850 0.73 CYP1A2 (0.30)
SCHEMBL21849410 0.71 TSHR (0.30) TSHRTDP1
SCHEMBL278294 0.69
SCHEMBL4338960 0.69 TBXAS1 (0.49) TSHRTDP1
SCHEMBL27687972 0.69
SCHEMBL24035225 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807644-B2 Methods and compounds for restoring mutant p53 function PMV PHARMACEUTICALS, INC. (US) 2023-11-07 US disclosed
CN-116710430-A Methods and compounds for restoring mutant p53 function 皮姆维制药公司 2023-09-05 CN disclosed
WO-2021231474-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION PMV PHARMACEUTICALS, INC. (US) 2021-11-18 WO disclosed
CN-102807520-A Ionic liquid and power storage device including the same SEMICONDUCTOR ENERGY LAB 2012-12-05 CN disclosed
US-8133898-B2 Renin inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-13 US disclosed
US-7557113-B2 Substituted pyrrolo[3,2-d]pyrimidine derivatives TEIJIN PHARMA LIMITED (JP) 2009-07-07 US disclosed
US-7557113-B2 Substituted pyrrolo[3,2-d]pyrimidine derivatives TEIJIN PHARMA LIMITED (JP) 2009-07-07 US disclosed
US-4906758-A Preparation of pyrroles from dialkoxytetrahydrofurans BASF AKTIENGESELLSCHAFT (DE) 1990-03-06 US disclosed
EP-0303206-A2 Process for the preparation of pyrroles BASF Aktiengesellschaft (DE) 1989-02-15 EP disclosed
EP-0125415-B1 PROCESS FOR THE PRODUCTION OF PYRROLES BASF Aktiengesellschaft (DE) 1986-11-26 EP disclosed
US-4560769-A CATALYTIC CYCLIZATION OF AMMONIA OR AMINE WITH BUT-2-ENE-1,4-DIOL BASF AKTIENGESELLSCHAFT (DE) 1985-12-24 US disclosed
EP-0125415-A1 Process for the production of pyrroles BASF Aktiengesellschaft (DE) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807644-B2 Methods and compounds for restoring mutant p53 function TP53, TP53BP1, HRAS TSHR 3729/4885TDP1 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.