Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164822 | 1.00 | GAA (0.60) | GAAMAPTCDC25BAHR | |
| SCHEMBL6246219 | 1.00 | GAA (0.60) | GAAMAPTCDC25BAHR | |
| Hydrochloric Acid SCHEMBL11071035 | 0.98 | GAA (0.58) | GAAMAPTCDC25BAHR | |
| Water SCHEMBL28741688 | 0.98 | GAA (0.58) | GAAMAPTCDC25BAHR | |
| Hydrochloric Acid SCHEMBL22617355 | 0.97 | GAA (0.57) | GAAMAPTCDC25BAHR | |
| SCHEMBL19066011 | 0.88 | GAA (0.62) | GAAMAPT | |
| SCHEMBL27930597 | 0.88 | GAA (0.62) | GAAMAPT | |
| SCHEMBL13889887 | 0.85 | GAA (0.42) | GAAMAPTCDC25BAHR | |
| SCHEMBL1760636 | 0.85 | SIRT1 (0.44) | GAAMAPTCDC25BAHR | |
| SCHEMBL13202969 | 0.85 | GAA (0.62) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283615-A | New Process and intermediate | PFIZER PROD INC (US) | 2001-02-14 | — | — | CN | claimed |
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | claimed |
| CN-1140709-A | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 1997-01-22 | — | — | CN | claimed |
| CN-103201276-B | Indole derivatives | RICHTER GEDEON NYRT | 2015-02-25 | — | — | CN | disclosed |
| CN-102015641-A | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2011-04-13 | — | — | CN | disclosed |
| EP-1330454-B1 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HITEK CO LTD (KR) | 2010-05-19 | — | — | EP | disclosed |
| CN-1740169-B | Arylmethylamine derivatives for use as tryptase inhibitors | AVENTIS PHARMA INC | 2010-04-21 | — | — | CN | disclosed |
| CN-100443482-C | Benzofuran derivatives and their use in the treatment of microbial infections | ARPIDA AG (CH) | 2008-12-17 | — | — | CN | disclosed |
| CN-101151245-A | Indan-amide derivatives with glycogen phosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | CN | disclosed |
| EP-1330454-A4 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2008-03-19 | — | — | EP | disclosed |
| CN-100374420-C | indole amide derivatives having glycogen phosphorylase inhibitory activity | ASTRAZENECA AB CO LTD (SE) | 2008-03-12 | — | — | CN | disclosed |
| CN-1140709-A | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 1997-01-22 | — | — | CN | disclosed |
| WO-1996039384-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| CN-1033031-C | Modified gangliosides and functional derivatives thereof | FIDIA SPA (IT) | 1996-10-16 | — | — | CN | disclosed |
| CN-1051912-A | Improved gangliosides and functional derivatives thereof | FIDIA B P A (IT) | 1991-06-05 | — | — | CN | disclosed |
| US-4479963-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |
| US-4374847-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |