Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 3/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015787 | 0.89 | HRH3 (0.44) | HRH3KDM1AHDAC4SLC6A4SLC6A3 | |
| SCHEMBL29900799 | 0.83 | TLR2 (0.48) | HRH3HDAC4ALDH1A1TLR2TLR1 | |
| SCHEMBL10311101 | 0.83 | MEN1 (0.48) | HRH3KDM1AHDAC4SLC6A4SLC6A3 | |
| SCHEMBL4342266 | 0.83 | ALDH1A1 (0.40) | TDP1HTR2AHTR2CHTR2BPDE4B | |
| SCHEMBL15054630 | 0.83 | ALDH1A1 (0.40) | TDP1HTR2AHTR2CHTR2BPDE4B | |
| SCHEMBL10277792 | 0.82 | PDE4B (0.57) | SLC6A4SLC6A3PDE4BPPARGPPARA | |
| SCHEMBL10277788 | 0.82 | PDE4B (0.57) | SLC6A4SLC6A3PDE4BPPARGPPARA | |
| SCHEMBL10277789 | 0.82 | PDE4B (0.57) | SLC6A4SLC6A3PDE4BPPARGPPARA | |
| SCHEMBL528422 | 0.79 | PDE4B (0.41) | HRH3KDM1AHDAC4SLC6A4SLC6A3 | |
| SCHEMBL528421 | 0.79 | PDE4B (0.41) | HRH3KDM1AHDAC4SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590942-A1 | RHO KINASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012006202-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |