Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.50 |
| ▸ | TDO2 | P48775 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12520453 | 0.73 | IDO1 (0.44) | IDO1TDO2ALDH1A1MAPTKMT2A | |
| SCHEMBL23836089 | 0.73 | IDO1 (0.46) | IDO1TDO2ALDH1A1MAPTKMT2A | |
| SCHEMBL7310972 | 0.73 | IDO1 (0.46) | IDO1TDO2ALDH1A1MAPTKMT2A | |
| SCHEMBL24740169 | 0.70 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPTKMT2A | |
| SCHEMBL24740261 | 0.70 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPTKMT2A | |
| SCHEMBL28057154 | 0.70 | CYP2D6 (0.37) | IDO1TDO2ALDH1A1 | |
| SCHEMBL1461839 | 0.69 | MAPT (0.56) | IDO1TDO2ALDH1A1MAPTKMT2A | |
| SCHEMBL262699 | 0.69 | CYP2C9 (0.47) | KMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5275526 | 0.68 | MAPT (0.51) | IDO1TDO2ALDH1A1MAPTKDM4E | |
| SCHEMBL19335741 | 0.68 | IDO1 (0.63) | IDO1TDO2MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100033295-A1 | HIGH TEMPERATURE THERMAL CUTOFF DEVICE | THERM-O-DISC, INCORPORATED (US) | 2010-02-11 | — | — | US | disclosed |