SCHEMBL3258159

SCHEMBL3258159

C=C[SiH2]CCCNC(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
CACNA2D1 P54289 1/20 0.32
HTR1B P28222 1/20 0.31
NR2E1 Q9Y466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268757 0.75
SCHEMBL2270078 0.71
SCHEMBL4540412 0.70
SCHEMBL2600364 0.69 HRH4 (0.43) HRH4HRH3CACNA2D1HTR1BNR2E1
SCHEMBL479263 0.69 HRH4 (0.39) HRH4HRH3CACNA2D1HTR1BNR2E1
SCHEMBL1243356 0.68 TSHR (0.42) HRH4HRH3
SCHEMBL841330 0.67 HRH4 (0.45) HRH4HRH3HTR1BNR2E1
SCHEMBL4789143 0.67 HRH4 (0.45) HRH4HRH3HTR1BNR2E1
SCHEMBL754871 0.67 HRH4 (0.45) HRH4HRH3HTR1BNR2E1
SCHEMBL19350614 0.67 HRH4 (0.45) HRH4HRH3HTR1BNR2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056711-A1 CONJUGATED DIENE POLYMER CONJUGATED DIENE POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-04 US disclosed