Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 9/20 | 1.00 |
| ▸ | FNTA | P49354 | 11/20 | 0.76 |
| ▸ | FNTB | P49356 | 11/20 | 0.76 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125313 | 0.86 | GRIA4 (1.00) | GRIA4FNTAFNTBGRIA2KMT2A | |
| SCHEMBL16792089 | 0.85 | FNTA (0.80) | GRIA4FNTAFNTBGRIA2KMT2A | |
| SCHEMBL16792274 | 0.85 | FNTA (1.00) | GRIA4FNTAFNTBKMT2A | |
| SCHEMBL3139252 | 0.85 | FNTA (0.79) | GRIA4FNTAFNTBGRIA2 | |
| SCHEMBL16798222 | 0.84 | FNTA (1.00) | GRIA4FNTAFNTBGRIA2KMT2A | |
| SCHEMBL3128889 | 0.83 | GRIA4 (1.00) | GRIA4FNTAFNTBGRIA2KMT2A | |
| SCHEMBL3137586 | 0.81 | GRIA4 (1.00) | GRIA4FNTAFNTBGRIA2KMT2A | |
| SCHEMBL5728529 | 0.81 | GRIA4 (0.73) | GRIA4FNTAFNTBGRIA2KMT2A | |
| SCHEMBL16798237 | 0.79 | FNTA (0.72) | GRIA4FNTAFNTBKMT2A | |
| SCHEMBL16792070 | 0.79 | FNTA (0.81) | GRIA4FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642361-B2 | Thiophene and furan compounds | ELI LILLY AND COMPANY (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642361-B2 | Thiophene and furan compounds | ELI LILLY AND COMPANY (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070105852-A1 | Thiophene and furan compounds | ELI LILLY AND COMPANY | 2007-05-10 | — | — | US | disclosed |
| US-20070105852-A1 | Thiophene and furan compounds | ELI LILLY AND COMPANY | 2007-05-10 | — | — | US | disclosed |
| WO-2005070916-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105852-A1 | Thiophene and furan compounds | PSEN2, PSEN1, TPMT | GRIA4 15/4885FNTA 1089/4885FNTB 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.