Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.73 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.73 |
| ▸ | FNTA | P49354 | 6/20 | 0.49 |
| ▸ | FNTB | P49356 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125313 | 0.84 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3134036 | 0.83 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3126306 | 0.82 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3128889 | 0.81 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3258244 | 0.81 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3138051 | 0.81 | GRIA4 (0.65) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3137586 | 0.79 | GRIA4 (1.00) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3136002 | 0.78 | GRIA4 (0.76) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL8282919 | 0.74 | GRIA4 (0.54) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL10656067 | 0.73 | GRIA4 (0.80) | GRIA4GRIA2FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706395-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005070916-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |