Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954734 | 0.75 | CHRM2 (0.45) | TAAR1MTORADKNISCHADRA2A | |
| SCHEMBL1845819 | 0.73 | KDM4E (0.46) | ADRA2AADRA2CKDM4E | |
| SCHEMBL3784547 | 0.73 | KDM4E (0.46) | ADRA2AADRA2CKDM4E | |
| SCHEMBL11384209 | 0.73 | TAAR1 (0.41) | FPR2TAAR1VDRMTORADK | |
| SCHEMBL812140 | 0.72 | FPR2 (0.69) | FPR2ADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL3667338 | 0.72 | FPR2 (0.48) | FPR2F2RL1 | |
| SCHEMBL5693691 | 0.72 | TAAR1 (0.46) | FPR2TAAR1MTORADKNISCH | |
| SCHEMBL7421358 | 0.72 | FPR2 (0.51) | FPR2 | |
| SCHEMBL16132513 | 0.71 | KCNA5 (0.45) | F7TDP1GAAALDH1A1 | |
| SCHEMBL17985414 | 0.71 | SCN1A (0.49) | TDP1GAAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076496-B1 | AMINOMETHYL-2-IMIDAZOLES WITH AFFINITY WITH THE TRACE AMINE ASSOCIATED RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-03-31 | — | — | EP | claimed |