Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3258684 | 1.00 | P2RX7 (0.64) | P2RX7SRD5A2PTGS2TSHRCASR | |
| SCHEMBL3248342 | 0.93 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL3248339 | 0.93 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL3248336 | 0.93 | P2RX7 (0.73) | P2RX7 | |
| Trifluoroacetic Acid SCHEMBL3258635 | 0.90 | P2RX7 (0.64) | P2RX7PTGS2 | |
| Trifluoroacetic Acid SCHEMBL3258632 | 0.90 | P2RX7 (0.64) | P2RX7PTGS2 | |
| Trifluoroacetic Acid SCHEMBL3253150 | 0.89 | P2RX7 (0.65) | P2RX7SRD5A2PTGS2 | |
| Trifluoroacetic Acid SCHEMBL3254056 | 0.89 | P2RX7 (0.81) | P2RX7PTGS2 | |
| Trifluoroacetic Acid SCHEMBL3254060 | 0.89 | P2RX7 (0.81) | P2RX7PTGS2 | |
| Trifluoroacetic Acid SCHEMBL3253143 | 0.89 | P2RX7 (0.65) | P2RX7SRD5A2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651613-B1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | AVENTIS PHARMA INC (US) | 2010-05-26 | — | — | EP | disclosed |