SCHEMBL3259642

SCHEMBL3259642

Cc1cccc2c1S(=O)(=O)NC2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
CA12 O43570 5/20 0.50
CA9 Q16790 5/20 0.50
CA4 P22748 4/20 0.50
CA7 P43166 4/20 0.50
KDM4E B2RXH2 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
BCHE P06276 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
KMT2A Q03164 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
SLC40A1 Q9NP59 1/20 0.48
DAO P14920 1/20 0.43
PDE7A Q13946 1/20 0.40
PDE7B Q9NP56 1/20 0.40
PARP1 P09874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193750 0.77 CA12 (0.50) CA1CA2CA12CA9CA4
SCHEMBL995389 0.77 CA12 (0.50) CA1CA2CA12CA9CA4
SCHEMBL1463156 0.77 CA9 (0.50) CA1CA2CA12CA9CA4
SCHEMBL230481 0.77 CA9 (0.50) CA1CA2CA12CA9CA4
SCHEMBL9179277 0.77 RET (0.53) CA1CA2CA12CA9CA4
SCHEMBL4080659 0.77 CA12 (0.46) CA1CA2CA12CA9CA4
SCHEMBL17049162 0.77 CA12 (0.46) CA1CA2CA12CA9CA4
SCHEMBL8547780 0.77 CA12 (0.46) CA1CA2CA12CA9CA4
SCHEMBL18726136 0.77 KMT2A (0.46) CA1CA2CA12CA9CA4
Saccharin SCHEMBL30211073 0.76 CA12 (0.81) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62063511-A None JP disclosed
JP-59216821-A None JP disclosed
CN-116270720-A Water-soluble chitosan polyelectrolyte complex, composition and application thereof 以勒企业股份有限公司 2023-06-23 CN disclosed
CN-218459469-U Alkoxylation ware 吉林瑞吉特殊化学品有限公司 2023-02-10 CN disclosed
CN-109715218-A For treating the composition and method of heart disease 嘉安生物治疗有限责任公司 2019-05-03 CN disclosed
US-20140301999-A1 BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS DECODE GENETICS EHF (IS) 2014-10-09 US disclosed
US-7674810-B2 1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase ROCHE PALO ALTO LLC (US) 2010-03-09 US disclosed
US-7651582-B2 Wood adhesives containing solid residues of biomass fermentations THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2010-01-26 US disclosed
US-20080202684-A1 Wood adhesives containing solid residues of biomass fermentations THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2008-08-28 US disclosed
US-20060235115-A1 Wood adhesives containing solid residues of biomass fermentations THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2006-10-19 US disclosed
US-20040259218-A1 Wood adhesives containing solid residues of biomass fermentations UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE, THE 2004-12-23 US disclosed
WO-2000000595-A1 INSECT CELL ENZYMES WITH α-GALACTOSYLTRANSFERASE ACTIVITY AND THEIR USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2000-01-06 WO disclosed
EP-0382120-B1 Method for producing biologically active polysaccharide ron substance SAPPORO BREWERIES (JP) 1995-05-24 EP disclosed
US-5332667-A Biosynthesis of antitumor SAPPORO BREWERIES LIMITED (JP) 1994-07-26 US disclosed
EP-0382120-A1 Method for producing biologically active polysaccharide ron substance SAPPORO BREWERIES LIMITED (JP) 1990-08-16 EP disclosed
JP-S6263511-A OXIDATION COLOR AGENT SHISEIDO CO LTD 1987-03-20 JP disclosed
JP-S59216821-A REMEDY AND PREVENTIVE FOR RESPIRATORY TRACT OBSTRUCTION EISAI CO LTD 1984-12-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140301999-A1 BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS PDE4A, PDE4B, PDE3B CA1 2284/4885CA2 1643/4885CA12 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.