SCHEMBL193750

SCHEMBL193750

Nc1cccc2c1S(=O)(=O)NC2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.50
CA9 Q16790 4/20 0.50
USP2 O75604 2/20 0.50
KMT2A Q03164 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 1/20 0.50
BCHE P06276 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
PDE7A Q13946 1/20 0.40
PDE7B Q9NP56 1/20 0.40
PARP1 P09874 2/20 0.40
PTPRC P08575 1/20 0.37
ADORA2A P29274 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7049683 0.87 CA12 (0.50) CA12CA9USP2KMT2ACA1
SCHEMBL9699937 0.79 CA12 (0.47) CA12CA9USP2KMT2ACA1
SCHEMBL1463156 0.77 CA9 (0.50) CA12CA9USP2KMT2ACA1
SCHEMBL995389 0.77 CA12 (0.50) CA12CA9USP2KMT2ACA1
SCHEMBL230481 0.77 CA9 (0.50) CA12CA9USP2KMT2ACA1
SCHEMBL3259642 0.77 CA1 (0.50) CA12CA9USP2KMT2ACA1
SCHEMBL9179277 0.77 RET (0.53) CA12CA9USP2KMT2ACA1
SCHEMBL6129786 0.77 CA12 (0.46) CA12CA9USP2KMT2ACA1
SCHEMBL6740547 0.76 CA12 (0.48) CA12CA9USP2KMT2ACA1
SCHEMBL9637088 0.76 CA12 (0.53) CA12CA9USP2KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380918-A1 PRODRUGS OF TAPINAROF Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) 2024-06-12 EP claimed
WO-2023014927-A1 PRODRUGS OF TAPINAROF ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) 2023-02-09 WO claimed
US-20220007639-A1 Arthropod Pest Control Compositions, Kits and Uses Thereof INSCENT, INC. (US) 2022-01-13 US claimed
US-11129380-B2 Arthropod pest control compositions, kits and uses thereof INSCENT, INC. (US) 2021-09-28 US claimed
US-10744355-B2 Heat resistant systems and methods GOODRICH CORPORATION (US) 2020-08-18 US claimed
EP-3648597-A1 ARTHROPOD PEST CONTROL COMPOSITIONS, KITS AND USES THEREOF Inscent, Inc. (US) 2020-05-13 EP claimed
EP-3630192-A1 WATER-SOLUBLE POLYSACCHARIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES Jointherapeutics S.r.l. (IT) 2020-04-08 EP claimed
CN-109338420-A A kind of neutral electrotinning electrolyte of environmental protection 江苏艾森半导体材料股份有限公司 2019-02-15 CN claimed
US-20190038653-A1 COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY DISEASES TETARD, INC. 2019-02-07 US claimed
WO-2018220537-A1 ADJUVANT SUPPLEMENT FOR ONCOLOGICAL PATIENTS RAVERA, Ugo (IT) 2018-12-06 WO claimed
WO-2001082971-A2 CYCLODEXTRIN CONTAINING GLYCOPEPTIDE ANTIBIOTIC COMPOSITIONS THERAVANCE, INC. (US) 2001-11-08 WO claimed
US-6183994-B1 SIMPLE METHOD BY REACTING MONO-, DI- OR OLIGOSACCHARIDE, GLYCOSIDE, OR DERIVATIVE WITH AMINODEOXY MONO-, DI-, OR OLIGOSACCHARIDE, OR GLYCOSIDE IN PRESENCE OF RECOMBINANT GLYCOSIDASE, THEN OPTIONALLY ISOLATING AMINO-DEOXY SACCHARIDE BIOFLEXIN AB (SE) 2001-02-06 US claimed
EP-0863761-A1 TOPICAL COMPOSITIONS CONTAINING A BETA-CYCLODEXTRIN AND AN AMINO POLYSACCHARIDE Everest-Todd Research & Development Ltd. (GB) 1998-09-16 EP claimed
WO-1997017977-A1 TOPICAL COMPOSITIONS CONTAINING A BETA-CYCLODEXTRIN AND AN AMINO POLYSACCHARIDE EVEREST-TODD RESEARCH & DEVELOPMENT LIMITED (GB) 1997-05-22 WO claimed
US-5563252-A REACTING AQUEOUS SOLUTION OF A SACCHARIDE AND AN AMINE WITH HYDROGEN IN PRESENCE OF CATALYST TO PRODUCE AMINOSACCHARIDE, REACTING INTERMEDIATE WITH 3-ISOPROPENYL-ALPHA-ALPHA-DIMETHYLBENZYLISOCYANATE NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1996-10-08 US claimed
EP-0533692-A4 MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF UNIV GEORGETOWN (US) 1995-03-22 EP claimed
EP-0533692-A1 MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF GEORGETOWN UNIVERSITY (US) 1993-03-31 EP claimed
US-5091523-A Bactericides, antitumor agent GEORGETOWN UNIVERSITY (US) 1992-02-25 US claimed
WO-1991016049-A1 MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF GEORGETOWN UNIVERSITY (US) 1991-10-31 WO claimed
US-4447562-A Amino-polysaccharides and copolymers thereof for contact lenses and ophthalmic compositions IVANI EDWARD J 1984-05-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038653-A1 COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY DISEASES TNF, PTGES, PTGES2 CA12 2010/4885CA9 1750/4885USP2 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.