Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 9/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.55 |
| ▸ | SOD3 | P08294 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8502193 | 0.98 | GNAO1 (0.62) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| Ammonia Solution, Strong SCHEMBL8502647 | 0.98 | GNAO1 (0.62) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL44569 | 0.98 | GNAO1 (0.61) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL9396737 | 0.98 | GNAO1 (0.61) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| Hydrochloric Acid SCHEMBL5370731 | 0.96 | GNAO1 (0.66) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL21581269 | 0.95 | GNAO1 (0.65) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL21581281 | 0.95 | GNAO1 (0.65) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL10379383 | 0.95 | GNAO1 (0.65) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL21581257 | 0.95 | GNAO1 (0.65) | GNAO1GNAI3GNAI1CXCR4SOD3 | |
| SCHEMBL21581298 | 0.95 | GNAO1 (0.65) | GNAO1GNAI3GNAI1CXCR4SOD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7651979-B2 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-01-26 | — | — | US | claimed |