Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720149 | 0.90 | NPSR1 (0.58) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL4291837 | 0.89 | NPSR1 (0.62) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL3260509 | 0.87 | L3MBTL1 (0.51) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL6172144 | 0.85 | NPSR1 (0.67) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL4854443 | 0.83 | NPC1 (0.67) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL2079861 | 0.82 | NPSR1 (0.64) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL22209257 | 0.82 | NPSR1 (0.64) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL20028758 | 0.82 | NPSR1 (0.64) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL22331103 | 0.81 | NPSR1 (0.86) | NPSR1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL20028759 | 0.81 | NPSR1 (0.59) | NPSR1MAPK1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |