Acrylonitrile

Acrylonitrile

SCHEMBL3260480

C=C(CC(CC)CCCC)C(=O)O.C=CC#N.C=CCC(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 2/20 0.34
LMNA P02545 1/20 0.34
CA2 P00918 3/20 0.33
CYP3A4 P08684 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL867425 0.92 TSHR (0.43) TSHRALDH1A1MAPK1LMNACA2
SCHEMBL3249371 0.92 TSHR (0.43) TSHRALDH1A1MAPK1CA2CYP3A4
Methacrylic Acid SCHEMBL16894607 0.88 TSHR (0.40) TSHRALDH1A1MAPK1LMNACA2
SCHEMBL15767897 0.87 TSHR (0.40) TSHRALDH1A1MAPK1CA2CYP3A4
SCHEMBL20609791 0.81 CA2 (0.47) TSHRALDH1A1MAPK1CA2CYP3A4
SCHEMBL22081 0.81 CA2 (0.47) TSHRALDH1A1MAPK1CA2CYP3A4
SCHEMBL9281566 0.80 TSHR (0.42) TSHRALDH1A1MAPK1CA2CYP3A4
Vinyl Chloride SCHEMBL10826111 0.80 TSHR (0.46) TSHRALDH1A1MAPK1CA2CYP3A4
Acrylic Acid SCHEMBL4419560 0.80 TSHR (0.50) TSHRALDH1A1MAPK1CA2CYP3A4
Ethylene SCHEMBL1759446 0.79 CA2 (0.46) TSHRALDH1A1MAPK1CA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221386-A1 GOLF BALL WITH INTERMEDIATE LAYER CONTAINING AN EXPANDABLE POLYMER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-09-03 US claimed
US-20060234812-A1 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY 2006-10-19 US claimed
US-20100292031-A1 GOLF BALL WITH INTERMEDIATE LAYER CONTAINING AN EXPANDABLE POLYMER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2010-11-18 US disclosed
US-7785217-B2 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY (US) 2010-08-31 US disclosed
US-20090221386-A1 GOLF BALL WITH INTERMEDIATE LAYER CONTAINING AN EXPANDABLE POLYMER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-09-03 US disclosed
US-7549936-B2 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY (US) 2009-06-23 US disclosed
US-20060234812-A1 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY 2006-10-19 US disclosed