Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200075 | 0.96 | GSR (0.37) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL3209598 | 0.81 | OTC (0.36) | — | |
| SCHEMBL3201591 | 0.80 | SMPD2 (0.31) | — | |
| SCHEMBL2981416 | 0.77 | CPB2 (0.39) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL2981409 | 0.77 | CPB2 (0.39) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL2981423 | 0.77 | CPB2 (0.39) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL3222384 | 0.77 | CPB2 (0.34) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL3222351 | 0.77 | CPB2 (0.34) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL3235889 | 0.75 | CPB2 (0.33) | CPB2GSRLMNACYP3A4NFKB1 | |
| SCHEMBL3235934 | 0.75 | CPB2 (0.33) | CPB2GSRLMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| US-7572776-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2009-08-11 | — | — | US | disclosed |
| US-20080306025-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2008-12-11 | — | — | US | disclosed |
| EP-1979366-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | Yu, Ruey J. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007082206-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J (US) | 2007-07-19 | — | — | WO | disclosed |