SCHEMBL3260748

SCHEMBL3260748

O=C(O)C=CC1(C=CC(=O)O)OC1(C=CC(=O)O)C=CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
TP53 P04637 1/20 0.44
EGLN1 Q9GZT9 1/20 0.44
EGLN3 Q9H6Z9 1/20 0.44
HCAR2 Q8TDS4 3/20 0.32
GABRR1 P24046 2/20 0.32
GABRR2 P28476 2/20 0.32
BLM P54132 2/20 0.32
GABRR3 A8MPY1 1/20 0.32
LMNA P02545 1/20 0.32
APEX1 P27695 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL105087 0.69
Fumaric Acid SCHEMBL4345647 0.69 TSHR (0.90) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL104720 0.69
Maleic Acid SCHEMBL4340878 0.69 TSHR (0.90) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL104719 0.69
Fumaric Acid SCHEMBL23387435 0.69 TSHR (0.90) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL3998225 0.65
Maleic Acid SCHEMBL613 0.65
Maleic Acid SCHEMBL20487516 0.65 TSHR (1.00) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL2046433 0.65 TSHR (1.00) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8588881-B2 Subcutaneous glucose electrode ABBOTT DIABETES CARE INC. (US) 2013-11-19 US disclosed
US-8414749-B2 Subcutaneous glucose electrode ABBOTT DIABETES CARE INC. (US) 2013-04-09 US disclosed
US-20100121166-A1 Subcutaneous Glucose Electrode ABBOTT DIABETES CARE INC. (US) 2010-05-13 US disclosed
US-20100072063-A1 Subcutaneous Glucose Electrode ABBOTT DIABETES CARE INC. (US) 2010-03-25 US disclosed
US-20100059373-A1 Subcutaneous Glucose Electrode ABBOTT DIABETES CARE INC. (US) 2010-03-11 US disclosed
US-20080210557-A1 SUBCUTANEOUS GLUCOSE ELECTRODE ABBOTT LABORATORIES (US) 2008-09-04 US disclosed
US-20070151869-A1 Subcutaneous Glucose Electrode ABBOTT DIABETES CARE, INC. (US) 2007-07-05 US disclosed