Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL23387435 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL104720 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL4345647 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL105087 | 1.00 | — | — | |
| Maleic Acid SCHEMBL4340878 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL615 | 0.95 | — | — | |
| Maleic Acid SCHEMBL613 | 0.95 | — | — | |
| Maleic Acid SCHEMBL20487516 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL3998225 | 0.95 | — | — | |
| Fumaric Acid SCHEMBL6875 | 0.95 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260097044-A1 | ION PAIR LIQUID CRYSTAL FORMULATIONS FOR LONG-ACTING INJECTABLES OF POORLY SOLUBLE DRUGS | FORDOZ PHARMA CORP. (US) | 2026-04-09 | — | — | US | claimed |
| EP-3825278-B1 | METHOD FOR PREPARING HIGH-PURITY BISFLUOROSULFONYLIMIDE SALT | SHANGHAI ROLECHEM CO LTD (CN) | 2025-12-17 | — | — | EP | claimed |
| US-20250273682-A1 | BINDER FOR ELECTRICITY STORAGE DEVICE, BINDER SOLUTION FOR ELECTRICITY STORAGE DEVICE, ELECTRODE SLURRY FOR ELECTRICITY STORAGE DEVICE, ELECTRODE FOR ELECTRICITY STORAGE DEVICE, AND ELECTRICITY STORAGE DEVICE | KURARAY CO., LTD. (JP) | 2025-08-28 | — | — | US | claimed |
| US-20250197778-A1 | STORAGE STABILIZATION AGENT FOR AQUEOUS HOME CARE FORMULATIONS | OMYA INTERNATIONAL AG (CH) | 2025-06-19 | — | — | US | claimed |
| EP-4540357-A1 | STORAGE STABILIZATION AGENT FOR AQUEOUS HOME CARE FORMULATIONS | Omya International AG (CH) | 2025-04-23 | — | — | EP | claimed |
| CN-119684502-A | Multifunctional adhesive, preparation method and application thereof | 华中科技大学 | 2025-03-25 | — | — | CN | claimed |
| US-20250087693-A1 | CATHODE ELECTRODE SHEET, A PREPARATION METHOD THEREOF AND A LITHIUM-ION BATTERY COMPRISING SAME | MURATA MANUFACTURING CO., LTD. (JP) | 2025-03-13 | — | — | US | claimed |
| CN-119601663-A | Positive electrode plate, preparation method thereof and lithium ion battery comprising positive electrode plate | 株式会社村田制作所 | 2025-03-11 | — | — | CN | claimed |
| CN-119505762-A | Polyacrylic acid binder, preparation method thereof and lithium ion battery | 万华化学集团电池科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119487165-A | Storage stabilizer for aqueous household care formulations | 欧米亚国际集团 | 2025-02-18 | — | — | CN | claimed |
| WO-2006060464-A1 | METHODS OF USING TEMOZOLOMIDE FORMULATION INTRATHECALLY IN THE TREATMENT OF CANCERS | SCHERING CORPORATION (US) | 2006-06-08 | — | — | WO | claimed |
| US-6987108-B2 | Pharmaceutical formulations of antineoplastic agents and processes of making and using the same | SCHERING CORPORATION (US) | 2006-01-17 | — | — | US | claimed |
| CN-1635871-A | pharmaceutical formulations of antineoplastic agents, in particular temozolomide, preparation method and use thereof | SCHERING CORP (US) | 2005-07-06 | — | — | CN | claimed |
| EP-1478339-A1 | PHARMACEUTICAL FORMULATIONS OF ANTINEOPLASTIC AGENTS, IN PARTICULAR TEMOZOLOMIDE, PROCESSES OF MAKING AND USING THE SAME | SCHERING CORPORATION (US) | 2004-11-24 | — | — | EP | claimed |
| US-20040043001-A1 | Pharmaceutical formulations of antineoplastic agents and processes of making and using the same | SCHERING CORPORATION | 2004-03-04 | — | — | US | claimed |
| WO-2003072082-A1 | PHARMACEUTICAL FORMULATIONS OF ANTINEOPLASTIC AGENTS, IN PARTICULAR TEMOZOLOMIDE, PROCESSES OF MAKING AND USING THE SAME | SCHERING CORPORATION (US) | 2003-09-04 | — | — | WO | claimed |
| US-20030111427-A1 | Composition for controlling the dissolving rate of solid sanitizers | ARCH CHEMICALS, INC. | 2003-06-19 | — | — | US | claimed |
| WO-2003032733-A1 | COMPOSITION FOR CONTROLLING THE DISSOLVING RATE OF SOLID SANITIZERS | ARCH CHEMICALS, INC. (US) | 2003-04-24 | — | — | WO | claimed |
| US-4040970-A | WITH COPOLYMER FOR RENDERING THE TONER NEGATIVELY CHARGEABLE | CANON KABUSHIKI KAISHA (JA) | 1977-08-09 | — | — | US | claimed |
| US-3977983-A | Liquid developer for use in development of an electrostatic latent image comprising a copolymer containing an amino group converted into a quaternary ammonium salt or hydroxide | CANON KABUSHIKI KAISHA (JA) | 1976-08-31 | — | — | US | claimed |