Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773 | 1.00 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL9011679 | 1.00 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL9011627 | 1.00 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044624 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL23356870 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL23356971 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044672 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044729 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044691 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044622 | 0.96 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101693709-A | Bicyclic amides as kinase inhibitors | NOVARTIS AG | 2010-04-14 | — | — | CN | disclosed |
| EP-2152658-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | Givaudan SA (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008116338-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | disclosed |
| CN-101018784-A | Bicyclic amides as kinase inhibitors | NOVARTIS AG (CH) | 2007-08-15 | — | — | CN | disclosed |