⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671581 | 0.67 | — | — | |
| SCHEMBL3264301 | 0.65 | — | — | |
| SCHEMBL8546999 | 0.65 | — | — | |
| SCHEMBL3314197 | 0.65 | — | — | |
| SCHEMBL8819890 | 0.64 | ALDH1A1 (0.31) | — | |
| SCHEMBL2875149 | 0.61 | — | — | |
| SCHEMBL220125 | 0.59 | — | — | |
| SCHEMBL5520093 | 0.59 | — | — | |
| SCHEMBL28956877 | 0.58 | — | — | |
| SCHEMBL5549399 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029606-B1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2010-05-26 | — | — | EP | claimed |
| EP-2029606-A2 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | Brystol-Myers Squibb Company (US) | 2009-03-04 | — | — | EP | claimed |
| US-7456167-B2 | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | claimed |
| WO-2007140254-A2 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-06 | — | — | WO | claimed |
| US-20070275947-A1 | Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-11-29 | — | — | US | claimed |
| US-20070248566-A1 | Antimicrobial polyisocyanate and derivatives thereof | HEADWAY ADVANCED MATERIALS INC. | 2007-10-25 | — | — | US | claimed |
| EP-1629864-A1 | Composition for dyeing keratin fibres comprising a methine direct dye with a benzoselenazolium group | L'OREAL (FR) | 2006-03-01 | — | — | EP | claimed |
| WO-1994006797-A1 | NOVEL BIOREDUCTIVE AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | claimed |
| US-4347246-A | Antihypertensive lactams | USV PHARMACEUTICAL CORPORATION (US) | 1982-08-31 | — | — | US | claimed |
| EP-2029606-B1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2010-05-26 | — | — | EP | disclosed |
| EP-2029606-A2 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | Brystol-Myers Squibb Company (US) | 2009-03-04 | — | — | EP | disclosed |
| US-7456167-B2 | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| WO-2007140254-A2 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070275947-A1 | Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-11-29 | — | — | US | disclosed |
| US-20070248566-A1 | Antimicrobial polyisocyanate and derivatives thereof | HEADWAY ADVANCED MATERIALS INC. | 2007-10-25 | — | — | US | disclosed |
| EP-1629864-A1 | Composition for dyeing keratin fibres comprising a methine direct dye with a benzoselenazolium group | L'OREAL (FR) | 2006-03-01 | — | — | EP | disclosed |
| US-20050043313-A1 | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2005-02-24 | — | — | US | disclosed |
| WO-1994006797-A1 | NOVEL BIOREDUCTIVE AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
| WO-1994006797-A1 | NOVEL BIOREDUCTIVE AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |