Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720542 | 0.75 | KDM4E (0.53) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL31214551 | 0.73 | MAPT (0.62) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| Lumichrome SCHEMBL29861572 | 0.68 | BLM (0.64) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| Lumichrome SCHEMBL29516827 | 0.68 | BLM (0.64) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| Lumichrome SCHEMBL194906 | 0.68 | BLM (0.64) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL5309140 | 0.65 | KDM4E (0.53) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL7822136 | 0.65 | BLM (0.47) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL2180718 | 0.64 | APAF1 (0.50) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL498704 | 0.64 | BLM (0.66) | KDM4EBLMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL4320247 | 0.64 | KDM4E (0.57) | KDM4EBLMTDP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014798-A2 | PYRIMIDOTRIAZINEDIONES AND PYRIMIDOPYRIMIDINEDIONES AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-02-04 | — | — | WO | disclosed |