⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326163 | 1.00 | — | — | |
| SCHEMBL319299 | 0.80 | — | — | |
| SCHEMBL319298 | 0.80 | — | — | |
| SCHEMBL6559760 | 0.78 | — | — | |
| SCHEMBL6559763 | 0.78 | — | — | |
| SCHEMBL319354 | 0.77 | — | — | |
| SCHEMBL325309 | 0.77 | — | — | |
| SCHEMBL319353 | 0.77 | — | — | |
| SCHEMBL325310 | 0.77 | — | — | |
| SCHEMBL8531968 | 0.77 | CASP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590968-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | Novartis AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109682-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2013-05-02 | — | — | US | disclosed |
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |
| US-6369223-B2 | USING CATALYST COMPLEX | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-04-09 | — | — | US | disclosed |
| US-20020004602-A1 | Asymmetric cycloaddition reactions | JACOBSEN ERIC N (US) | 2002-01-10 | — | — | US | disclosed |
| US-6211370-B1 | REACTING A DIENOPHILE WITH A 1,3-DIENE | HARVARD UNIVERSITY | 2001-04-03 | — | — | US | disclosed |
| WO-2000050365-A1 | ASYMMETRIC CYCLOADDITION REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-1999036375-A1 | ASYMMETRIC CYCLOADDITION REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-07-22 | — | — | WO | disclosed |