Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL3261820

C=CCN(CC=C)C(=S)S.S.S.[Mo]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.40
CYP2E1 P05181 1/20 0.40
PTGS1 P23219 1/20 0.40
HTT P42858 1/20 0.40
GSDMD P57764 1/20 0.40
ALDH1A1 P00352 4/20 0.38
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
KCNH2 Q12809 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
CCR6 P51684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL14994756 0.97 ABCB11 (0.42) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL2360254 0.97 ABCB11 (0.42) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL30903 0.95 HTT (0.43) ABCB11CYP2E1PTGS1HTTGSDMD
Ammonia Solution, Strong SCHEMBL8733451 0.92 HTT (0.42) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL21594656 0.92 ABCB11 (0.42) ABCB11CYP2E1PTGS1HTTGSDMD
Hydrochloric Acid SCHEMBL11788090 0.92 ABCB11 (0.42) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL8517488 0.92 ABCB11 (0.42) ABCB11CYP2E1PTGS1HTTGSDMD
Zinc Ion SCHEMBL16209435 0.90 ABCB11 (0.40) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL5979774 0.88 ABCB11 (0.39) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL11821244 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200115650-A1 Constant Velocity Joint Having A Boot FUCHS PETROLUB SE (DE) 2020-04-16 US disclosed
US-20170145340-A1 Constant Velocity Joint Having A Boot FUCHS PETROLUB SE (DE) 2017-05-25 US disclosed
US-8603958-B2 Calcium/lithium complex greases and encapsulated constant velocity joint containing the grease and method for their production FUCHS PETROLUB AG (DE) 2013-12-10 US disclosed
US-20120302472-A1 Lubricating Greases Containing Lignosulfonate, The Production Thereof, and the Uses Thereof FUCHS PETROLUB AG (DE) 2012-11-29 US disclosed
US-20100048436-A1 Calcium/Lithium Complex Greases and Encapsulated Constant Velocity Joint Containing the Grease and Method for their Production FUCHS PETROLUB AG (DE) 2010-02-25 US disclosed