Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 14/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350219 | 0.96 | SLC6A9 (0.53) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1348714 | 0.94 | SLC6A9 (0.40) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1348674 | 0.92 | SLC6A9 (0.51) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1348719 | 0.89 | SLC6A9 (0.57) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1349513 | 0.88 | SLC6A9 (0.56) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1349692 | 0.87 | SLC6A9 (0.55) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL3262198 | 0.87 | SLC6A9 (0.49) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1348082 | 0.86 | SLC6A9 (0.43) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1349517 | 0.86 | SLC6A9 (0.42) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL1350061 | 0.85 | SLC6A9 (0.42) | SLC6A9CYP2D6CYP2C19SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020548-A1 | GLYT1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-25 | — | — | WO | disclosed |