Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 15/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262360 | 0.91 | PROKR1 (0.46) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL3264724 | 0.85 | ALDH1A1 (0.55) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL325537 | 0.84 | PROKR1 (0.39) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL1722509 | 0.81 | PROKR1 (0.47) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL20394962 | 0.79 | ALDH1A1 (0.61) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL3268298 | 0.78 | HPGD (0.44) | LMNAALDH1A1HPGDNPC1MAPT | |
| SCHEMBL304021 | 0.75 | PROKR1 (0.49) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL3264723 | 0.75 | ALDH1A1 (0.55) | PROKR1LMNAALDH1A1HPGDHIF1A | |
| SCHEMBL3237608 | 0.73 | GRM5 (0.75) | ALDH1A1HPGDNPC1MAPTRAB9A | |
| SCHEMBL3235160 | 0.72 | GRM5 (0.49) | ALDH1A1NPC1MAPTRAB9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023445-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |