SCHEMBL3262680

SCHEMBL3262680

OC1CN(Cc2ccc(-c3ccccc3)cc2)CC1O

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.68
GBA1 P04062 1/20 0.57
CYP2D6 P10635 2/20 0.55
HRH4 Q9H3N8 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53
S1PR1 P21453 5/20 0.51
S1PR5 Q9H228 5/20 0.51
KCNH2 Q12809 1/20 0.51
CYP2C19 P33261 1/20 0.50
FAAH O00519 1/20 0.50
S1PR4 O95977 1/20 0.49
CHKA P35790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30287840 0.93 FUCA1 (0.74) FUCA1GBA1CYP2D6HRH4HRH3
SCHEMBL1857553 0.93 FUCA1 (0.80) FUCA1GBA1CYP2D6HRH4HRH3
SCHEMBL24008565 0.93 FUCA1 (0.74) FUCA1GBA1CYP2D6HRH4HRH3
SCHEMBL2268869 0.93 FUCA1 (0.80) FUCA1GBA1CYP2D6HRH4HRH3
SCHEMBL2272254 0.89 FUCA1 (0.58) FUCA1GBA1CYP2D6HRH4HRH3
SCHEMBL20017877 0.88 FUCA1 (0.85) FUCA1GBA1S1PR1S1PR5
SCHEMBL562632 0.88 FUCA1 (0.85) FUCA1GBA1S1PR1S1PR5
SCHEMBL84802 0.88 FUCA1 (0.85) FUCA1GBA1S1PR1S1PR5
SCHEMBL71063 0.88 FUCA1 (0.85) FUCA1GBA1S1PR1S1PR5
SCHEMBL5155562 0.88 FUCA1 (0.85) FUCA1GBA1S1PR1S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010029313-A1 ANTIINFECTIVE COMPOUNDS SUMMIT CORPORATION PLC. (GB) 2010-03-18 WO disclosed