SCHEMBL71063

SCHEMBL71063

O[C@@H]1CN(Cc2ccccc2)C[C@H]1O

nearest known ligand 0.85

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.85
GBA1 P04062 1/20 0.69
SIGMAR1 Q99720 2/20 0.58
ALDH1A1 P00352 1/20 0.58
S1PR1 P21453 1/20 0.56
S1PR5 Q9H228 1/20 0.56
SLC18A3 Q16572 1/20 0.53
MAPT P10636 1/20 0.51
GRIN1 Q05586 1/20 0.51
GRIN2B Q13224 1/20 0.51
ACHE P22303 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL84802 1.00 FUCA1 (0.85) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL562632 1.00 FUCA1 (0.85) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL20017877 1.00 FUCA1 (0.85) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL5155562 1.00 FUCA1 (0.85) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
Hydrochloric Acid SCHEMBL10840201 0.98 FUCA1 (0.81) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL15599205 0.92 FUCA1 (0.92) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL7637770 0.92 FUCA1 (1.00) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL15599027 0.92 FUCA1 (0.92) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL17181666 0.92 FUCA1 (0.92) FUCA1GBA1SIGMAR1ALDH1A1S1PR1
SCHEMBL15599028 0.92 FUCA1 (0.92) FUCA1GBA1SIGMAR1ALDH1A1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493628-A Quantum dot ink and preparation method of quantum dot film TCL科技集团股份有限公司 2021-10-12 CN claimed
CN-113122053-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
US-20180009841-A1 METHOD FOR PREPARING NANOPRECIPITATES OF LOW MOLECULAR WEIGHT PEPTIDE OR PROTEIN CARLINA TECHNOLOGIES (FR) 2018-01-11 US claimed
EP-2990033-A1 Process of nanoprecipitation of proteins and peptides with low molecular weight Carlina Technologies (FR) 2016-03-02 EP claimed
EP-3275448-B1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES KYOWA KIRIN CO LTD (JP) 2025-10-29 EP disclosed
WO-2025099451-A1 NEW COMPOUNDS AND METHODS Transition Bio Limited (GB) 2025-05-15 WO disclosed
CN-114507215-B Compound serving as PAK4 kinase inhibitor and preparation method and application thereof 成都海博为药业有限公司 2024-09-13 CN disclosed
US-20240132500-A1 METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS ARRAY BIOPHARMA INC (US) 2024-04-25 US disclosed
US-20230234955-A1 METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS ARRAY BIOPHARMA INC (US) 2023-07-27 US disclosed
CN-113493628-B Quantum dot ink and preparation method of quantum dot film TCL科技集团股份有限公司 2023-06-23 CN disclosed
US-11633365-B2 Nucleic acid-containing lipid nanoparticle KYOWA KIRIN CO., LTD. (JP) 2023-04-25 US disclosed
US-11566029-B2 Pyrazolo[1,5-a]pyrimidine-5,7-diamine compounds as CDK inhibitors and their therapeutic use IP2IPO INNOVATIONS LIMITED (GB) 2023-01-31 US disclosed
EP-1346982-A1 VLA-4 INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-09-24 EP disclosed
US-6573377-B1 Antitumor agent capable of showing its efficacy even against 5- FU drug resistant tumors DAIICHI PHARMACEUTICALS CO., LTD. (JP) 2003-06-03 US disclosed
EP-1103551-A1 PYRAZOLE DERIVATIVES AND SALTS THEREOF DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-05-30 EP disclosed
WO-2000023444-A1 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 2000-04-27 WO disclosed
EP-0973738-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 2000-01-26 EP disclosed
US-5952363-A Pyrrolidine compounds useful in the treatment of diabetes NOVO NORDISK A/S (DK) 1999-09-14 US disclosed
WO-1998040353-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1998-09-17 WO disclosed
US-5585500-A Method of producing optically active pyrrolidines with high enantiomeric purity DEGUSSA AKTIENGESELLSCHAFT (DE) 1996-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633365-B2 Nucleic acid-containing lipid nanoparticle LIPA, LIPC, PNLIP FUCA1 906/4885GBA1 128/4885SIGMAR1 2946/4885
US-20240132500-A1 METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS TYMP, TYMS, P2RX7 FUCA1 1734/4885GBA1 111/4885SIGMAR1 963/4885
US-20230234955-A1 METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS TYMP, TYMS, TK1 FUCA1 2462/4885GBA1 202/4885SIGMAR1 1679/4885
US-11566029-B2 Pyrazolo[1,5-a]pyrimidine-5,7-diamine compounds as CDK inhibitors and their therapeutic use CDK10, CDK1, CDK20 FUCA1 3993/4885GBA1 4215/4885SIGMAR1 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.