Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307842 | 0.84 | LMNA (0.42) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL1814085 | 0.83 | KCNJ6 (0.37) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL3306636 | 0.83 | KMT2A (0.36) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL1814487 | 0.81 | KDM4E (0.40) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL1816105 | 0.81 | KDM4E (0.44) | NTRK1GAAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL3299180 | 0.81 | HTT (0.40) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL3261317 | 0.78 | NTRK1 (0.38) | NTRK1HPGDALDH1A1HTTLMNA | |
| SCHEMBL11163620 | 0.74 | NAPRT (0.34) | GAATSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL15717788 | 0.71 | NTRK1 (0.85) | NTRK1GAATSHRKCNJ6KCNJ5 | |
| SCHEMBL16595134 | 0.70 | NTRK1 (1.00) | NTRK1GAATSHRKCNJ6KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020366-A1 | AZABICYCLIC SUBSTITUTED 5-AMINOPYRAZOLES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-25 | — | — | WO | disclosed |