Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 10/20 | 0.33 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.32 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.31 |
| ▸ | S100A10 | P60903 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963005 | 0.86 | SREBF2 (0.36) | SREBF2KDR | |
| SCHEMBL2964082 | 0.76 | SREBF2 (0.44) | SREBF2 | |
| SCHEMBL2970865 | 0.75 | SREBF2 (0.36) | SREBF2 | |
| SCHEMBL2968573 | 0.71 | SYK (0.40) | SREBF2KDR | |
| SCHEMBL2968113 | 0.68 | KDM4E (0.35) | SREBF2SREBF1 | |
| SCHEMBL15268008 | 0.67 | KDM4E (0.37) | SREBF2ROCK1SREBF1 | |
| SCHEMBL2965361 | 0.66 | SREBF2 (0.44) | SREBF2KDR | |
| SCHEMBL2961153 | 0.66 | SREBF2 (0.44) | SREBF2 | |
| SCHEMBL17613404 | 0.66 | IDO1 (0.39) | SREBF2 | |
| SCHEMBL2961869 | 0.66 | PIM1 (0.42) | RIPK2SREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979349-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2010-07-28 | — | — | EP | disclosed |