Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 7/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268008 | 0.89 | KDM4E (0.37) | KDM4ELMNACYP3A4TSHRHTR1A | |
| SCHEMBL15290719 | 0.88 | IDO1 (0.40) | IDO1KDM4ELMNAHTR1AADRA1D | |
| SCHEMBL13230482 | 0.84 | SREBF2 (0.42) | IDO1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL15268009 | 0.83 | HTR1A (0.38) | IDO1KDM4EHTR1AADRA1DADRA1A | |
| SCHEMBL13330355 | 0.80 | HTR1A (0.38) | IDO1KDM4ELMNAHTR1AADRA1D | |
| SCHEMBL15268011 | 0.80 | HTT (0.41) | IDO1KDM4ELMNAHTR1AADRA1D | |
| SCHEMBL17613400 | 0.78 | TRPV1 (0.39) | IDO1LMNAHTR1AADRA1DADRA1A | |
| SCHEMBL2970208 | 0.78 | KDM4E (0.42) | IDO1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL2961850 | 0.78 | KDM4E (0.39) | KDM4ELMNACYP3A4TSHRHSD17B10 | |
| SCHEMBL17613403 | 0.75 | CXCR4 (0.43) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367824-B1 | Anti-viral derivatives of pyrimidine | ABBVIE INC (US) | 2016-03-23 | — | — | EP | disclosed |