SCHEMBL3262956

SCHEMBL3262956

Cc1cc(N(C)C)ccc1C(O)c1ccc(N(C)C)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
ALDH1A1 P00352 6/20 0.40
TSHR P16473 4/20 0.40
ALOX15 P16050 3/20 0.40
HSD17B10 Q99714 1/20 0.40
TERT O14746 1/20 0.38
APP P05067 1/20 0.38
APAF1 O14727 1/20 0.36
CRHR1 P34998 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36
MCL1 Q07820 1/20 0.36
KDM4E B2RXH2 3/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
G6PD P11413 1/20 0.35
SLC2A1 P11166 1/20 0.34
HPGD P15428 1/20 0.34
CYP3A4 P08684 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL962867 0.83 MAPT (0.46) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL38662618 0.83 MAPT (0.46) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL3193700 0.83 MAPT (0.46) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL13385286 0.81 ALDH1A1 (0.46) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL25340875 0.78 GAA (0.38) MAPTALDH1A1TSHRAPAF1CRHR1
SCHEMBL8777562 0.78 ESR1 (0.47) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL10349015 0.78 KMT2A (0.40) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL28603532 0.77 MAPT (0.42) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL5009553 0.76 SLC2A1 (0.47) MAPTALDH1A1TSHRALOX15HSD17B10
SCHEMBL10776452 0.76 MAPT (0.41) MAPTALDH1A1TSHRALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217110-B2 bleachable dye comprising Michler's hydrol cation acidified with a non-nucleophilic anion, after bleaching Michler's hydrol became colorless; blue color visible glues when applying, become colorless after curing; prevent bonding of skin, unintended surface area; polymerizing, curing ethyl-2-cyanoacrylate 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-07-10 US disclosed
US-8217110-B2 bleachable dye comprising Michler's hydrol cation acidified with a non-nucleophilic anion, after bleaching Michler's hydrol became colorless; blue color visible glues when applying, become colorless after curing; prevent bonding of skin, unintended surface area; polymerizing, curing ethyl-2-cyanoacrylate 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-07-10 US disclosed
EP-2069446-B1 COLOR CHANGE CYANOACRYLATE ADHESIVES 3M INNOVATIVE PROPERTIES CO (US) 2010-03-17 EP disclosed
US-20090317561-A1 COLOR CHANGE CYANOACRYLATE ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY 2009-12-24 US disclosed
EP-2069446-A1 COLOR CHANGE CYANOACRYLATE ADHESIVES 3M Innovative Properties Company (US) 2009-06-17 EP disclosed
US-20080075862-A1 COLOR CHANGE CYANOACRYLATE ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY 2008-03-27 US disclosed
US-20080075862-A1 COLOR CHANGE CYANOACRYLATE ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY 2008-03-27 US disclosed
WO-2008030903-A1 COLOR CHANGE CYANOACRYLATE ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-03-13 WO disclosed
EP-0486749-A1 Triarylmethane compounds and pressure sensitive recording material HODOGAYA CHEMICAL CO., LTD. (JP) 1992-05-27 EP disclosed