⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775718 | 0.98 | — | — | |
| SCHEMBL1830619 | 0.98 | — | — | |
| SCHEMBL57052 | 0.98 | — | — | |
| SCHEMBL4543595 | 0.93 | KDM4E (0.47) | — | |
| SCHEMBL5372700 | 0.93 | KDM4E (0.47) | — | |
| SCHEMBL218863 | 0.82 | FOLH1 (0.39) | — | |
| SCHEMBL5729609 | 0.82 | FOLH1 (0.39) | — | |
| SCHEMBL6398091 | 0.82 | KDM4E (0.42) | — | |
| SCHEMBL7447971 | 0.75 | ACE (0.47) | — | |
| SCHEMBL19971886 | 0.74 | TGFBR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7651697-B2 | Nitric oxide-producing hydrogel materials | RICE UNIVERSITY (US) | 2010-01-26 | — | — | US | disclosed |
| US-7279176-B1 | Nitric oxide-producing hydrogel materials | RICE UNIVERSITY (US) | 2007-10-09 | — | — | US | disclosed |
| US-20060153795-A1 | Nitric oxide-producing hydrogel materials | RICE UNIVERSITY | 2006-07-13 | — | — | US | disclosed |
| US-7052711-B2 | Nitric oxide-producing hydrogel materials | RICE UNIVERSITY (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1315476-A2 | NITRIC OXIDE-PRODUCING HYDROGEL MATERIALS | Rice University (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20030012816-A1 | Nitric oxide-producing hydrogel materials | RICE UNIVERSITY | 2003-01-16 | — | — | US | disclosed |
| EP-1194171-A2 | NITRIC OXIDE-PRODUCING HYDROGEL MATERIALS | Rice University (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2002017880-A2 | NITRIC OXIDE-PRODUCING HYDROGEL MATERIALS | RICE UNIVERSITY (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001015738-A2 | NITRIC OXIDE-PRODUCING HYDROGEL MATERIALS | RICE UNIVERSITY (US) | 2001-03-08 | — | — | WO | disclosed |