Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Tolylamine SCHEMBL5315045 | 0.94 | FFAR3 (0.52) | ALDH1A1KDM4EMAPTFFAR3SMN1; SMN2 | |
| SCHEMBL5065033 | 0.87 | FFAR3 (0.72) | KDM4EFFAR3SMN1; SMN2 | |
| SCHEMBL5315047 | 0.86 | FFAR3 (0.60) | ALDH1A1KDM4EMAPTFFAR3SMN1; SMN2 | |
| SCHEMBL5201411 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTFFAR3SMN1; SMN2 | |
| SCHEMBL15859370 | 0.82 | FFAR3 (0.57) | ALDH1A1KDM4EMAPTFFAR3SMN1; SMN2 | |
| SCHEMBL3263495 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTFFAR3SMN1; SMN2 | |
| SCHEMBL5064866 | 0.73 | FFAR3 (0.76) | KDM4EFFAR3SMN1; SMN2 | |
| SCHEMBL5202041 | 0.72 | FFAR3 (0.76) | ALDH1A1KDM4EMAPTFFAR3SMN1; SMN2 | |
| SCHEMBL5197527 | 0.72 | FFAR3 (0.60) | ALDH1A1KDM4EFFAR3SMN1; SMN2LMNA | |
| SCHEMBL2849024 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1KDM4EFFAR3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030997-A1 | REGULATING INTESTINAL MICROBIOTA DEPENDENT SIGNALING AS A MEANS TO MODULATE BODY FAT AND/OR WEIGHT LOSS | THE WASHINGTON UNIVERSITY (US) | 2010-03-18 | — | — | WO | disclosed |