Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778042 | 0.74 | GRIA2 (0.48) | MEN1TTRALBKMT2AGRIA2 | |
| SCHEMBL2777399 | 0.60 | MEN1 (0.32) | MEN1TTRALBKMT2A | |
| SCHEMBL24316721 | 0.57 | HTR2C (0.36) | — | |
| SCHEMBL20906149 | 0.57 | CYP11B1 (0.37) | MEN1TTRALBKMT2A | |
| SCHEMBL25716555 | 0.56 | TTR (0.42) | MEN1TTRALBKMT2A | |
| SCHEMBL22938645 | 0.55 | MEN1 (0.38) | MEN1TTRALBKMT2A | |
| SCHEMBL28438701 | 0.54 | TTR (0.61) | MEN1TTRALBKMT2A | |
| SCHEMBL20906125 | 0.53 | XDH (0.45) | MEN1TTRALBKMT2A | |
| SCHEMBL24129430 | 0.53 | TTR (0.58) | MEN1TTRALBKMT2A | |
| SCHEMBL15406588 | 0.53 | TTR (0.58) | MEN1TTRALBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004139-A1 | NEW CYCLOALKYLATED BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2010-01-14 | — | — | WO | disclosed |