Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2241929 | 0.97 | BDKRB1 (0.39) | BDKRB1MEN1KMT2AMAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL2236181 | 0.96 | BDKRB1 (0.40) | BDKRB1MAPTLMNAALDH1A1PPARA | |
| Trifluoroacetic Acid SCHEMBL1936321 | 0.96 | BDKRB1 (0.40) | BDKRB1MAPTLMNAALDH1A1PPARA | |
| SCHEMBL12346709 | 0.93 | BDKRB1 (0.42) | BDKRB1MEN1KMT2AMAPTLMNA | |
| SCHEMBL12346708 | 0.91 | BDKRB1 (0.43) | BDKRB1MEN1KMT2AMAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL302389 | 0.83 | BDKRB1 (0.47) | BDKRB1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2240006 | 0.81 | BDKRB1 (0.56) | BDKRB1MEN1KMT2AMAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL2236229 | 0.80 | PKM (0.44) | MEN1KMT2ALMNASMN1; SMN2CXCR3 | |
| SCHEMBL2236107 | 0.80 | BDKRB1 (0.43) | BDKRB1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2237280 | 0.80 | BDKRB1 (0.57) | BDKRB1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020556-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2010-02-25 | — | — | WO | claimed |