Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 11/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264514 | 1.00 | CAMK2D (0.43) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL13309649 | 0.86 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL3227477 | 0.86 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL13309648 | 0.86 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL3421997 | 0.86 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL3264612 | 0.86 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL3420476 | 0.84 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL3234459 | 0.84 | CAMK2D (0.45) | CAMK2DPLK1LDHALDHBSYK | |
| SCHEMBL3420513 | 0.75 | MAPT (0.38) | CAMK2DSYKMAPTVCP | |
| SCHEMBL3235616 | 0.74 | SYK (0.40) | SYKMAPTVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |