Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976235 | 0.86 | CNR2 (0.44) | HDAC4MEF2DALOX12NTRK1NAMPT | |
| SCHEMBL3263684 | 0.85 | KDM1A (0.50) | NAMPTMAPK1SMN1; SMN2HDAC1LMNA | |
| SCHEMBL3262613 | 0.85 | HDAC4 (0.45) | HDAC4MEF2DALOX12NTRK1NAMPT | |
| SCHEMBL3262741 | 0.82 | KDR (0.38) | HDAC4MEF2DNAMPTRAB9ANPC1 | |
| SCHEMBL1964857 | 0.82 | HDAC4 (0.54) | HDAC4MEF2DALOX12NTRK1L3MBTL1 | |
| SCHEMBL318081 | 0.76 | DRD4 (0.39) | — | |
| SCHEMBL3263279 | 0.76 | DRD4 (0.50) | GAAMAPTALDH1A1MAPK1 | |
| SCHEMBL3261430 | 0.75 | HTR2C (0.40) | HDAC4MEF2DNTRK1L3MBTL1GAA | |
| SCHEMBL1964227 | 0.72 | HDAC4 (0.60) | HDAC4MEF2DALOX12L3MBTL1GAA | |
| SCHEMBL11935851 | 0.72 | JAK2 (0.51) | HDAC4MEF2DALOX12NAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |