Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263275 | 0.87 | TSHR (0.50) | DRD4TRPV1POLBKMT2ATP53 | |
| SCHEMBL318081 | 0.82 | DRD4 (0.39) | DRD4TRPV1PARP1POLBKMT2A | |
| SCHEMBL1966404 | 0.78 | DRD4 (0.51) | DRD4TRPV1POLBKMT2ADRD2 | |
| SCHEMBL1964857 | 0.78 | HDAC4 (0.54) | MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL3263689 | 0.76 | HDAC4 (0.49) | MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL306481 | 0.75 | PARP1 (0.42) | DRD4TRPV1PARP1POLBKMT2A | |
| SCHEMBL3262613 | 0.73 | HDAC4 (0.45) | MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL1970405 | 0.71 | PKM (0.59) | PARP1POLBKMT2APKMMAPT | |
| SCHEMBL29893671 | 0.71 | PKM (0.59) | PARP1POLBKMT2APKMMAPT | |
| SCHEMBL6909954 | 0.70 | DRD4 (0.80) | DRD4TRPV1PARP1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |